DEA Warns 'Synthetic Soup' of Fentanyl Mixtures Is Overwhelming Naloxone
Law enforcement reports fentanyl increasingly combined with xylazine, medetomidine, nitazenes and cychlorphine—substances that resist naloxone reversal.
May 17, 20265 min read
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Single Dose of Psilocybin Shows Rapid Antidepressant Effects in Swedish Trial
First randomized double-blind study in Sweden finds psilocybin provides clinically meaningful depression relief within days, with 53% remission rate at six weeks.
May 17, 20265 min read
Delaware Senate Passes Harm Reduction Bill Amid Partisan Debate
Senate Bill 249 decriminalizes drug paraphernalia possession and expands sterile supply distribution, sparking disagreement over public safety and addiction treatment approaches.
May 16, 20265 min read
Single Psilocybin Dose Produces Lasting Brain Changes, Study Finds
UC San Francisco and Imperial College London researchers discover that one 25mg dose of psilocybin creates measurable anatomical brain changes lasting at least a month.
May 16, 20265 min read
Michigan Launches First-of-Its-Kind Opioid Settlement Tracking System
Michigan Attorney General Dana Nessel unveils comprehensive spending guidance and public reporting tools to ensure opioid settlement funds reach communities in need.
May 15, 20264 min read
Telepsychiatry's Rural Promise Falls Short, JAMA Study Finds
Despite rapid expansion of telehealth mental health services, a major JAMA study reveals only modest gains in reaching rural and underserved patients.
May 15, 20265 min read
Arizona Audit Finds $50.9 Million in Opioid Settlement Funds Misused for Prison Hepatitis C Treatment
State auditor finds Arizona Department of Corrections may have unlawfully spent opioid settlement money without proving inmates contracted hepatitis C from IV drug use.
May 14, 20266 min read
US Overdose Deaths Fall 14% in 2025, Marking Third Consecutive Year of Decline
CDC reports nearly 70,000 overdose deaths in 2025, a 14% drop and the longest sustained decline in decades, though challenges remain in several states.
May 14, 20266 min read
Orphines and Cychlorphine: The Next Wave of Synthetic Opioids Threatening to Reverse Overdose Declines
As overdose deaths finally begin to fall, a new class of ultra-potent synthetic opioids is emerging in the US drug supply, presenting unprecedented challenges for detection and treatment.
May 13, 20268 min read