Medication-Assisted Treatment (MAT) Treatment Centers
Medication-Assisted Treatment (MAT) combines FDA-approved medications with counseling and behavioral therapies to treat substance use disorders. For opioid addiction, medications like buprenorphine (Suboxone), methadone, and naltrexone (Vivitrol) reduce cravings and withdrawal symptoms, significantly improving treatment outcomes. For alcohol use disorder, medications like naltrexone, acamprosate, and disulfiram help maintain sobriety. Research shows MAT reduces overdose deaths, improves treatment retention, and increases the likelihood of long-term recovery. Despite stigma, MAT is considered the standard of care for opioid use disorder.
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Showing 4 of 6244 medication-assisted treatment (mat) treatment centers

Zinnia Exeter, located in the heart of Exeter, Rhode Island, stands out as a leading rehabilitation center dedicated to helping individuals on their journey to recovery from substance use disorders. With a strong commitment to quality care, the center offers a variety of specialized services tailored to meet diverse needs. At Zinnia Exeter, clients can access essential services such as hospital inpatient detoxification, which provides a safe environment for individuals to cleanse their bodies of substances, and 24-hour inpatient care that ensures continuous support and medical attention. For those who require more extended help, long-term residential treatment options are also available, allowing individuals to immerse themselves in a structured recovery environment. One of the distinctive features of Zinnia Exeter’s approach is its emphasis on evidence-based methods, including 12-step facilitation—a guiding framework for many in recovery. In addition, the center offers programs in anger management and brief intervention strategies, recognizing that these aspects are often crucial for long-term healing. The facility is dedicated to serving a broad spectrum of clients, including adult men and women, as well as individuals who have faced the challenges of intimate partner violence or domestic violence. This inclusive approach means that Zinnia Exeter caters to adults and young adults of all genders, ensuring that everyone feels welcome and supported. By focusing on comprehensive care and fostering an environment conducive to healing, Zinnia Exeter continues to be a vital resource for individuals taking meaningful steps toward sobriety. If you or someone you know is seeking assistance, the compassionate team at Zinnia Exeter is ready to help guide you through the recovery process.
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Nestled in Glen Oaks, NY, Zucker Hillside Hospital Northwell stands out for its dedicated rehabilitation services that cater specifically to individuals grappling with substance use issues, as well as those facing serious co-occurring mental health disorders. This facility doesn’t stop there; it also provides support for children dealing with emotional disturbances, recognizing the importance of addressing mental health at all ages. At Zucker Hillside Hospital, the outpatient care options are designed to meet a variety of needs. Among these services are methadone and buprenorphine treatments, as well as regular outpatient programs tailored to fit individual circumstances. The facility employs a range of approaches, such as 12-step facilitation, anger management techniques, and brief intervention strategies, all aimed at fostering healing and recovery. What truly sets this center apart is its commitment to catering to adult men and women, including those who have experienced intimate partner violence. Zucker Hillside understands that recovery is not one-size-fits-all; therefore, it offers personalized treatment plans based on evidence-based practices, ensuring that both adults and young adults of all genders receive the support they need for meaningful and lasting recovery.
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ZION Integrated Behavioral Health Services, located in the heart of Shenandoah, IA, is dedicated to providing a broad spectrum of substance use treatment options that cater specifically to adults and seniors. The center has designed its programs to be flexible and adaptable, offering intensive outpatient, outpatient, and regular outpatient treatment formats, each carefully tailored to meet the unique needs of every individual. What sets ZION apart is its commitment to personalized care, with specialized programs that address the needs of different groups such as adolescents, adult men, and adult women. This thoughtful approach ensures that clients receive the support and understanding they deserve throughout their recovery journey. At ZION, the focus is on holistic recovery, employing evidence-based methodologies that have proven to be effective in guiding individuals towards a healthier future. These methods include 12-step facilitation, anger management, and brief intervention strategies, all of which work together to create a comprehensive treatment experience. Moreover, ZION Integrated Behavioral Health Services is proud to offer its services to both male and female clients, recognizing the importance of providing quality care that is responsive to the specific challenges faced by each gender. In a welcoming environment, ZION aims to support those seeking effective addiction treatment, ensuring that each individual receives the attention and care necessary for lasting recovery.
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Situated in the heart of Clarinda, Iowa, ZION Integrated Behavioral Health Services stands out as a vital resource for those on the journey to recovery from substance use and co-occurring mental health disorders. This facility prides itself on offering a wide array of treatment options that cater to the diverse needs of its clients, including specialized programs tailored for adults, seniors, and young adults, and welcoming individuals of all genders. ZION Integrated Behavioral Health Services employs evidence-based practices that have been shown to be effective in promoting recovery. Among these are cognitive behavioral therapy and anger management, both of which are integral components of their treatment plans. The center is flexible in its approach, providing various levels of care, such as intensive outpatient programs, regular outpatient services, and even transitional housing solutions to help individuals as they progress in their recovery. A particularly noteworthy aspect of ZION Integrated Behavioral Health Services is its emphasis on addressing the unique challenges faced by clients who have encountered trauma or experienced intimate partner violence. The facility is dedicated to ensuring that each person receives personalized care tailored to their specific circumstances. This commitment to individualized treatment fosters an environment conducive to both lasting recovery and improved emotional well-being.
View DetailsAbout Medication-Assisted Treatment (MAT)
Medication-Assisted Treatment is the gold-standard, evidence-based approach for opioid use disorder, endorsed by the World Health Organization, SAMHSA, and the American Society of Addiction Medicine. According to NIDA, MAT reduces opioid overdose deaths by more than 50%. Despite this, only about 18% of the 2.5 million Americans with opioid use disorder receive MAT (SAMHSA 2023 National Survey on Drug Use and Health), representing a critical treatment gap.
Understanding MAT
Medication-Assisted Treatment combines FDA-approved medications with counseling and behavioral therapies. MAT is not "replacing one drug with another"—it is medical treatment for a chronic brain disorder that normalizes brain chemistry, reduces cravings, and allows individuals to focus on recovery.
FDA-Approved Medications for Opioid Addiction
- Buprenorphine (Suboxone, Subutex): A partial opioid agonist that reduces cravings and withdrawal. Can be prescribed by certified physicians in office settings.
- Methadone: A full opioid agonist dispensed through specialized clinics. Highly effective for severe addiction.
- Naltrexone (Vivitrol): An opioid blocker available as daily pills or monthly injection. Prevents opioid effects if someone uses.
FDA-Approved Medications for Alcohol Addiction
- Naltrexone: Reduces cravings and the pleasurable effects of alcohol
- Acamprosate (Campral): Helps maintain abstinence by reducing discomfort from not drinking
- Disulfiram (Antabuse): Creates unpleasant effects if alcohol is consumed
Why MAT Works
Research consistently shows MAT:
- Reduces overdose deaths by 50% or more
- Improves treatment retention significantly
- Reduces illicit drug use
- Decreases criminal activity
- Improves employment outcomes
- Reduces transmission of infectious diseases
Combining MAT with Therapy
MAT is most effective when combined with counseling and behavioral therapies. Treatment centers offering MAT typically also provide individual therapy, group counseling, CBT, and connections to support groups.
Addressing Stigma
Despite strong evidence, MAT faces stigma from some who view it as not "true recovery." Medical and addiction specialists, however, recognize MAT as essential healthcare. Just as diabetics take insulin, people with opioid addiction may need medication to maintain recovery.
What to Expect with MAT
MAT follows a structured medical protocol:
- Phase 1: Medical Assessment (Days 1–3) — Comprehensive evaluation including physical exam, substance use history, and medication selection. Medically managed detox may begin simultaneously
- Phase 2: Induction (Days 3–7) — Careful medication initiation under medical supervision. For buprenorphine, this requires a specific withdrawal state before starting. Methadone begins at low doses with gradual increases
- Phase 3: Stabilization (Weeks 2–8) — Dose optimization while beginning counseling and CBT or other behavioral therapies. Transition to intensive outpatient if appropriate
- Phase 4: Maintenance (Months 3+) — Ongoing medication management via standard outpatient, regular counseling, and recovery support. Duration varies — many experts recommend at least 12 months, some indefinitely
Treatment Outcomes & Research
A landmark study in The Lancet found MAT reduces all-cause mortality among people with opioid use disorder by 50%. The New England Journal of Medicine reported that buprenorphine doubles 12-month retention in treatment compared to placebo. The CDC confirms that expanding MAT access is the single most effective strategy for reducing opioid overdose deaths, which claimed over 80,000 lives in the U.S. in 2023.
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Insurance & Payment for Medication-Assisted Treatment (MAT)
The Mental Health Parity and Addiction Equity Act (MHPAEA) and the Affordable Care Act (ACA) require most health insurance plans to cover substance use disorder and mental health treatment at the same level as medical and surgical care. This means medication-assisted treatment (mat) is typically covered when deemed medically necessary.
Coverage varies by plan and provider. Many treatment centers accept private insurance, Medicaid, Medicare, TRICARE, and offer sliding-scale fees. Contact your insurance company or the treatment center directly to verify benefits.
Helpful resources:
- Learn about insurance coverage for rehab
- Explore standard outpatient programs (often most affordable)
- Consider telehealth services for accessible, lower-cost options
- SAMHSA National Helpline — free, confidential, 24/7 referrals (1-800-662-4357)
- Medicaid.gov — check eligibility for state Medicaid coverage
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Medical Disclaimer
This content is for informational purposes only and does not constitute medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before making decisions about addiction treatment. If you or someone you know is in crisis, contact the 988 Suicide & Crisis Lifeline (call or text 988) or the SAMHSA National Helpline (1-800-662-4357).